Cite TridentSynth

Please reference the following works when describing TridentSynth in your publications.

1. Chainani, Y., Bonnanzio, G., Tyo, K. E. J., & Broadbelt, L. J. (2023). Coupling chemistry and biology for the synthesis of advanced bioproducts. Current Opinion in Biotechnology, 84, 102992.
2. Chainani, Y., Ni, Z., Shebek, K. M., Broadbelt, L. J., & Tyo, K. E. J. (2025). DORA-XGB: an improved enzymatic reaction feasibility classifier trained using a novel synthetic data approach. Molecular Systems Design & Engineering, 10(2), 129–142.
3. Chainani, Y., Diaz, J., Guilarte-Silva, M., Blay, V., Zhang, Q., Sprague, W., Tyo, K. E. J., et al. (2025). Merging the computational design of chimeric type I polyketide synthases with enzymatic pathways for chemical biosynthesis. Nature Communications, 16(1), 5787.
4. Zhang, Q., Sprague, W. W., Kozarekar, S. S., Pate, S. C., Uekert, T., & Broadbelt, L. J. (2025). Discovery of hybrid chemical synthesis pathways with DORAnet. Digital Discovery, 4(11), 3109–3125.

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